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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a00792424cb744df6908d1bd828f77b4d8adbbeedf80d9493543f78fdb65adc' 
  AND token = '8gVZ9zw3VC9/1w4vmL0aOTJU3pHkT8k+QLklI23Mx0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}