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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '628bed38f19b93b1d6be9eeba25ed11b3dd4857e63a74d09694aed208bca5221' 
  AND token = '4d5paNzyQ7Cha1VTc/9a1/FSx0qSZI38gzKqqEPDqQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}