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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15be441d4328a468cf4d6c2d4690847ec2acaa50cf41878c4a5dd63233e4ce4c' 
  AND token = '6Sjs2fVKbPgDogRlYV8uhHtLt+sYcJRPbAWjuUvo0Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}