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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b329ea8ebc8c510903e17a9a8aec61f189562cb152a7a38c76be6e5a458cb889' 
  AND token = 'wi3ltZLypFjXRgtrzffvfhyTev+V5F1Fwh1VYVmTvlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}