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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3372ab6a02b0c5857ff6bd0174102c734424be35543054a58be4b1b31a23831' 
  AND token = '5gzeJGVEwQPVEOxsNxcfXSrHLUX2U1jeNQ4DZXvuWxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}