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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d7650ec29b53127451fd52d77cb7d0d476f1e07e03b1d903d4a89a241ed767f' 
  AND token = 'Nvvk1mwWl7jmePpgqIkM5fGuC3h7OZvi/NVfZ8FOOxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}