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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b58fb0ad6870a13469a7bf4b84ee3deb3a80364c48448553ea29d3cf968d5f4' 
  AND token = 'os05AVadRxxQzn1SqAT1fJqatb0M5nVx5+Uj+0igSEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}