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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cd2a7dfcf5dd30b8b0b3b92ad9c7016218f8a877aea765803bfae5579fa9e0f' 
  AND token = 'N4Sz8RU/jUCf2V65/eltPEM1ROJv2K6K1Cwyg1tIMGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}