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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b220797294164ccd2295cd6a3519b7c8ee1cf230fbf87ccb8a01bc90a2ac4eaf' 
  AND token = 'TeTiF4FQiYfkhbTqcnv6DeT3TUT5wRsqyYm1SGis3Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}