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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e632ff0b88045746c66e6d683529afe7dfcd0ac1230a606b40c0066c4d6ddd6' 
  AND token = 'CKgY3Jx/9qNSZFF/e5ZvKQSxgaJFiwXx653Ny0f2cXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}