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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '724e5449e59b5a58df15c18d98e857f47e0ab03ddbbfff6a6eb4ebaf77729614' 
  AND token = '2Ja3LPhRn9MzUtRdU+S3a+hyhOFS/Cq+rTFHIBcIgPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}