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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8166f46ac600700b2998f998895a71c3daed595a332208bfdc3de06f5524f6b6' 
  AND token = 'lAI97xHEud/ZYFUbr0l6AIHrbDWrHeU0FD9r4BUQuro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}