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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfccd346166810fc6a2f5f8cff0d28219bb47c09f7216986a9c29edbd0235cd3' 
  AND token = 'EVwoRIku0HDC+/XlhfqIgg1grem+5sQh/+HkzNl3iuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}