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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f679e64200b30a88a1bc29458c71c24c5a9f538cd1b71b01a2d46f123ca51ee' 
  AND token = 'Uma0FXo/QSVEeZsRtp7Q4SYkfSzJIFSBmanFDAkPnJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}