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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a4a1dbbfee2e5b2f9f40c3cf5b1caf1e242a1ad27f3be6c3734812e2f9e8cb5' 
  AND token = 'niDU/3cnYLBsqMC8Q9/Pp+zdV+z1yg7dGbnSIyZOYDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}