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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f747375fef3b1892d6ad5bc463fdcfbe39c1e4624e9d3cf8aa1333c51ad1a1' 
  AND token = 'cUFq/kziXPC8RLHuimDTXBq2OdhZ7QJ6PxsZTfZxsto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}