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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a9971a7e702d829879185f59b6bf67f09c574af0680bac4a2fd4f4777d5688' 
  AND token = 'STeJfmP0FKXipZzTaRn5JikvQEB+3yGblS2bJOsEcKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}