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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cec2eb96a9ce11f429fe880c06358ac0645acf27090a0980f456bbd8ba4e4090' 
  AND token = 'Sn1md/EnxxZxXEOJmgIM77m1Xdhp9t6Tbu2WB11Wh0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}