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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2711a7d7f6c2a6f7bad2802cee07666c20b6306f41a8517f7f105e03e6cc416' 
  AND token = 'kWbtsxJvxHrWE8k2BfUxjOH0ZDpiHb0HVg75ppM3+CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}