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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '172219a0025b4545a53733eeb1a06102d1027133ff5ed16cc208f66e08fa6e6d' 
  AND token = 'a1Y3qFwDuNU/LQqELDySZraZ4ZSo5y3ajn8EzPPk18c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}