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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9957874a900a89540db6cdee74c075a22b41b91933f44c82fcf69f9f3e2f64a' 
  AND token = 'uagk7MBWoOrJDAsw1NX642rF5Yip6/pjrh0oH89+0N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}