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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b81a7117d7c4554b9b8c5d4519fea339b95e7eba4aa3a245087444a8c18b51b' 
  AND token = 'CzsXi4hx4J1rqekqi74JD0mKIRhn4vgjR2iP9kX+0Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}