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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e808ace5d6bf7158787e95dae8196d2504451654ecf9e9529f90f9ee548579' 
  AND token = 'RphcRc0PngDvMh9RZS57Z+NElQWssh7WNJflHns7FDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}