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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49b6c17e94b448a5b0f144d02db8634e8e99785c6e752a1edb0c0d8a8f883f4' 
  AND token = 'CdXDL1vv7ntDcoKi8AAVu15T0mFJShC2Ob9AFVHt6YQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}