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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d86d67c20ec8529816e84c8eb225244a3452218806b2d0d7a4db354994e1f5d' 
  AND token = 'icmcau+OgtJSOrZN/9KBLBQCEL0W1jpkXBEfYr2Dxnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}