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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357b280a9f7d6ce9296068aae08bbe20f1aa4e7fcd24d3297601f6922bab49ca' 
  AND token = 'MxcVi6dkjb9c349Qc5hJNYk3g6VcrsA0U8rpk93HsM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}