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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cad0382aad9d2394abb3e7eafea3f54c9de368b65fd5c762f51d4011c7174aa' 
  AND token = '9cvpap6xXXygH/QOHBm0v0baka+3YPMlWyHCcqZJfJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}