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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72239c7e2827e2c9b80dc9a8bc32b2d0e920adfbf40535587d716d65084783a0' 
  AND token = 'qXzV5mmkzK1l8gd54oW+3o41x2/HW3KVpF3chr1Anms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}