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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aa912d21b039e11acbec20a492c7b3617bd0c8d4be6009c9f350e41c42f0582' 
  AND token = 'U4UowcmseGBK+PY1zfqTfI9GxhFXgfQ0hejXuXJUcAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}