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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd00f3dc3e9723a7dbad75e8185350658530d4ce2655f05c74d08671cbf8f5c1d' 
  AND token = 'DZ6r25uWMgLTthf2Ig3BelSBvnyYeFZO1B7PUS3Xyrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}