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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8ae4df9c51965e45bcc9b12adba2df642ed59bc846290dae1d8af2db6ab1323' 
  AND token = 'oyGy847/J/oeP/Jgb48Cl6NgBfsrZc8JiGIFC6jW3HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}