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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '521d68f9c640078eed0a3e1e23dbbf9dd1beaa30b9f162b829599ffc7a2ba324' 
  AND token = 'I6kBbHE44RilQuVtIffz/PZe7elwod8RZ4vO/t2lvkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}