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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8438a6ed2ef52754514dd6cc25c7ee6060140dcbff3c20e67e1e345159f2055a' 
  AND token = 'RwE0i1WXY3F5LDAo/EiT3BaQubx+zO9bDjaSHkvdG5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}