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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2373fbe9c3d859a7fd0f5869cff27750afa5ba6dd023a76996734ce41621afd9' 
  AND token = 'ps4FAQDdFJwh9PF3W7LsRNe1Owck5IKJ+Tw6jpxrmE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}