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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a72752a778ccad34dc6f22787b0f0456b9130fc4c70726a67a911176763056f' 
  AND token = '8NZVUN/w8s0nqBnA+QW4GnHgpPd+Ih728UeQykrNJ8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}