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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08824dd63f770a6e8414a39c680fea9d63e176cebabc59fa3981b2b9e424fda0' 
  AND token = 'nGSeeT8hQtaff21bgMul08hqvut7+zAsNVDnf5cgAqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}