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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e0008ac013aed919cfa0799a0399c84dc2ce514d72f9559e1486733d0308c3' 
  AND token = '2mSiLj/EN9NhPzH36MUqY9LDBKkRMwm6dMeQoaE2qlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}