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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '373a8e4d81c3ff04b7bde838d7ad9fc0a035a5c16d42f5fb8f719353b39ee20c' 
  AND token = 'OxU5B6Rs6kDt7hNB4Xt66pDJSbICBAZHFavNovC0B5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}