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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2b4318880d47562bde80d8f758c4431d6859b8883fa5dea36a34a03fce01f1' 
  AND token = 'uZ6MmaJA0zD/+tkYNbQTxTvV+5CJnq/FQkA1UPcwWhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}