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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4c29557ba7a739ef25921be54a0bc4ce8e64201dbf40f99f955a7509625cc3' 
  AND token = '6j7E6tvD679D2KQw/uVJyKP+v14bxKZyueOPbuG5YYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}