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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e6c06ede901550d47c305ee37bd09a9424373288c395b984ce17bc25e89a142' 
  AND token = 'lNsPsqFJvXOAvNehUxaUA8ikq79Ms+bwdY1Pmf/gOCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}