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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2377a19d11ec6f3be90640f6d9d5d256ea992a7c087c4a158eaef47ce54e264c' 
  AND token = 'vdooLIBLmGo95rdG5203DRAmmIlea354aePvEZsVWS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}