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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e04be59a3bd9c2b46f4757eb04e2cc12054b299d0b6ea359b98191b17762d0b0' 
  AND token = '+zqeBt52YeB5/noLWXIfFrlPjbc0BroONgHDGih1lZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}