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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70c404739b78b04b9f73e4f35c6fb90ed6e8ccb60f37317d06044253523fa374' 
  AND token = 'GPt3NKd9rJP/Vr98J6cdHcPG3JryC+CSEuItsp8i0Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}