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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dc3092109cb92f4cbeb120eac26a69a1ecd943777e7e5c40dabafcb0661ffc2' 
  AND token = 'FMsIG2xpY6+dGwaQc/LgHEbmG5N6Pj9iDVFnoBtJnGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}