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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd606722e5c340dd7e29c2a88df099dc170009991c667b529aab92ea0e78b8f' 
  AND token = 'Bl6bLoT7cfInOgL9u93p28iYuAaAIAB2AdRPYuo8WWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}