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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4afee0c4a1052d928dc57f39457ae92250e3e23a6bb931cc3ea3c766a6c6d4' 
  AND token = '2ZwxYlqG6iJWv70M53UZNXT0DGZu8nIq77iZlGTkPZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}