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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ca195eea0c25143c9cb89ec48f03a34121a4b01fa4f3f8430c9e60c46a455e0' 
  AND token = 'PFz7UaWz8zL9AM/47ys8y4ML4tM/Sf8NvLBnwEGNUn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}