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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '715dd4dc9a988bd1f7aab33857c33a59d72a1bc69371d58f3caa6471f05cda88' 
  AND token = 'UKV9vbPO2IhfrZKxmTYDC30y6/LYdbF1yhWFC8Lqtqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}