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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc1a6aba1741d9f29fdf42202de33d8021034ca2de80d12904dee648e934287a' 
  AND token = 'L1/nXobA9tpeyxhLSdiJFP/mLUQ4wpmFHL8gT7HmmFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}